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KMID : 0043320210440070725
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Archives of Pharmacal Research
2021 Volume.44 No. 7 p.725 ~ p.740
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Is loss of smell an early predictor of COVID-19 severity: a systematic review and meta-analysis
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Purja Sujata
Shin Ho-Cheol
Lee Ji-Yun
Kim Eun-Young
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Abstract
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Anecdotal evidence suggests that the severity of coronavirus disease of 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is likely to be distinguished by variations in loss of smell (LOS). Thus, we conducted a meta-analysis of 45 articles that include a total of 42,120 COVID-19 patients from 17 different countries to demonstrate that severely ill or hospitalized COVID-19 patients have a lesser chance of experiencing LOS than non-severely ill or non-hospitalized COVID-19 patients (odds ratio?=?0.527 [95% CI 0.373?0.744; p?
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KEYWORD
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COVID-19, SARS-CoV-2, Anosmia, COVID-19 severity, COVID-19 hospitalization
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